Clinically available KRAS inhibitors mainly target G12C, which is rare in PDAC and often acquires resistance. Oncogenic KRAS inactivates RB1 via CDK4/6, while RB1 mutation is rare. Thus, CDK4/6 ...

Discover the latest industry insights at the 2026 Annual Meeting through engaging educational and product-focused sessions. These presentations give exhibiting companies a platform to unveil ...

Type 1 diabetes (T1D) is an autoimmune disease characterized by the immune-mediated destruction of pancreatic B cells. While autoreactive T cells are key ...

Microglia (immune cells) and the RANK protein are essential for triggering puberty and maintaining fertility in the brain.

Northwestern Medicine scientists have discovered how calcium signaling channels in microglia—the primary immune cells of the brain—regulate neuroinflammation and promote the development of behaviors ...

A team of researchers has shown that noninvasive electrical stimulation of the vagus nerve through the ear can reverse memory ...

Chronic disease research increasingly points to the centrality of metabolic remodeling and mitochondrial dysfunction in dictating disease onset, severity, ...

This important study advances our understanding of developmental timing mechanisms by studying the cleavage, nuclear translocation, and oscillation of the transcription factor MYRF-1 (vertebrate MYRF) ...

Immunome is advancing varegacestat for desmoid tumors, targeting NDA submission in Q2 2026 after positive phase 3 RINGSIDE ...

Barclays 28th Annual Global Healthcare Conference March 10, 2026 8:30 AM EDTCompany ParticipantsDaniel Faga - President, CEO ...

Study Identifies Two Effective Treatment Approaches for Heart Valve Patients A major international study has found that two common treatments for ...