The mitochondria, perhaps better known as the powerhouses of cells, are emerging as a possible factor in the pains of aging.

Researchers found that the cells of young adults with depression overproduce energy while resting but struggle to respond to ...

Chronic disease research increasingly points to the centrality of metabolic remodeling and mitochondrial dysfunction in dictating disease onset, severity, ...

Many people chalk up persistent fatigue and constant sugar cravings to a “slow metabolism,” but according to physician Dr. Phuong Vo, what’s actually happening beneath the surface is far more complex.

Coenzyme A, a molecule derived from vitamin B5, is vital for metabolism throughout the body. Scientists discovered that most of it resides inside mitochondria, yet how it reached these cellular ...

Researchers create a massive single-cell atlas of the aging mouse brain, revealing how epigenetic changes and "jumping genes" drive neurodegeneration.

Neuropathic pain is a devastating type of pain that significantly reduces the quality of life of affected people.

The first cell rejuvenation therapy is set to enter clinics, testing if aging cells can be reset to a younger, healthier ...

You will be redirected to our submission process. DRAFT Reproductive success depends on precisely coordinated molecular and cellular signaling across sperm function, oocyte maturation, fertilization, ...

Neurodegenerative diseases affect more than 57 million people globally. The incidence of these diseases, from Alzheimer's to Parkinson's to ALS and beyond, is expected to double every 20 years. Though ...

Salk researchers create epigenetic atlas of cell type-specific changes in the aging mouse brain, representing eight different brain regions and 36 different cell types to show clear epigenetic ...

Restoring the gut microbiota through fecal microbiota transplantation reversed these effects. The treatment replenished CX3CR1-positive NK cells, reduced lung damage, and improved survival. Targeted ...