The centrosome, consisting of a pair of centrioles and pericentriolar material (PCM), is the major microtubule-organizing centre (MTOC) of many eukaryotic cells. Centrosome duplication and MTOC ...

The centrosome is a small, non-membrane-bound organelle endowed with the remarkable capacity to nucleate and organize microtubules. It consists of a pair of centrioles — structures analogous to the ...

The cover for issue 26 of Oncotarget features Figure 6, "Mislocalization of IQGAP1-BRCA1 in human TNBC tumors phenocopies the dominant mutants and the TNBC cells," by Osman, et al. and reported that ...

Non Adherence to Post Surgery Annual Surveilance Mammogram and Follow Up Among Breast Cancer Survivors in a Tertiary Care Hospital in Malaysia Modern chemotherapeutics frequently suffer from selective ...

Centrosomes are small structures in cells with many essential functions, including roles in cell signaling and in organizing a cell’s cytoskeleton. Centrosome dysfunction contributes to diseases like ...

A recent Cell Reports paper by the Oxenius group (IMB) demonstrates a function of targeted centrosome inheritance during CD8+ T cell division for the generation of memory precursor cells.

Researchers from the DZNE have solved an important puzzle in neurobiology: the wiring and the movement of nerve cells are interwoven, but separately controlled. The study focuses on neuronal growth ...

The centrosome is the organelle responsible for the organization of the cytoskeleton during cell division, an essential function in organisms from yeast to humans. Until now, scientists assumed that ...

In humans and other mammals, cardiac muscle cells stop replicating soon after birth, unlike the cardiac muscle cells in, say, zebrafish and amphibians. What do zebrafish and amphibian cardiomyocytes ...

When cells extend, move, or divide, a tiny organelle called the centrosome provides a cytoskeletal anchor and regulatory hub. It was long held that centrosomes are similar in composition across cells.

When a cell is dividing, two identical structures, called centrosomes, move to opposite sides of the cell to help separate its chromosomes into the new cells. When a cell is dividing, two identical ...