Secondary infections caused by bacteria or viruses during hospital care remain a long-standing global challenge, despite advances in modern medicine. In particular, mixed bacterial–viral infections in ...

FDA Fast Track designation has been granted to CTx001 for Geographic Atrophy secondary to Age-related Macular Degeneration CTx001 is an investigational AAV-based gene therapy designed to modulate ...

Abstract: In immune systems, the innate immune response and CD8 T cells play a crucial synergistic role in combating viral pathogens. In this paper, we develop a delayed viral infection model to ...

Immunological memory research has previously referred only to the adaptive immune system and its responses to pathological triggers. This was challenged, however, by a study in innate immune memory, ...

Complement 3 glomerulopathy (C3G) is a rare kidney disease that affects your body’s innate immune system (complement system). Complement 3 glomerulopathy (C3G) is a kidney disease that’s caused by ...

The objective of this study was to evaluate the methodology to establish the hemolytic activity of alternative complement pathway as an indicator of the innate immunity in Brazilian fish pacu ...

Combating viral infections has become a paramount global concern. Elucidating antiviral immune mechanisms is essential for developing antiviral strategies. Accumulating evidence indicates the vital ...

Mannose-binding lectin (MBL) is a critical serum protein of the innate immune system that recognises distinct carbohydrate signatures on pathogens, initiating the lectin pathway of the complement ...

Scientists at the University of Pennsylvania have uncovered the mathematical rules that govern one of the body’s oldest and most important immune system defenses, the complement system, according to ...

Expert Rev Clin Immunol. 2008;4(3):379-390. Since there are no genetic deficiencies of CRP in man, animal models have been used to study the role of CRP in inflammatory disease. Two methods have been ...

In the past, immune memory was considered an exclusive feature of the adaptive immune system. However, accumulating evidence suggests that the innate immune system, the most primitive and fundamental ...