After acute injury to the brain, neurons at the damage epicentre depolarize, and this depression of activity spreads outward in waves through the cortex. A recently published study sheds light on how ...

这篇综述深入探讨了扩散性去极化（Spreading Depolarization, SD）与偏头痛先兆及头痛期的因果关系，提出SD通过激活三叉神经伤害感受器、诱发硬脑膜炎症等机制参与偏头痛发作，并论证了靶向SD的防治潜力，为偏头痛药物研发提供了新思路。 摘要 偏头痛先兆 ...

Researchers have discovered a new mechanism that contributes to cell death after a subarachnoid hemorrhage (SAH), providing a new target for therapeutic intervention. The mechanism — known as ...

People with temporal lobe epilepsy in particular often wander around aimlessly and unconsciously after a seizure. Researchers at the University Hospital Bonn (UKB), the University of Bonn, and the ...

Scientists now confirmed a mechanism in mouse, bat and naked mole rat cells -- a 'mild depolarization' of the inner mitochondrial membrane -- that is linked to aging: Mild depolarization regulates the ...