Fat-based vesicles help deliver GM1 to the brain, improving movement and extending survival in mouse models of ALS, a study finds.

The origin of the nucleus remains hotly debated among scientists, but new imaging and genomic data are shedding light on this billion-year-old mystery.

Dendritic cells (DCs) are increasingly recognized as important contributors to sepsis-associated immune dysfunction.

Spinal cord injury often triggers a cascade of secondary damage that severely limits functional recovery, largely driven by ...

Sepsis remains a major challenge in modern medicine, claiming millions of lives each year. For decades, clinical management has largely focused on suppressing excessive inflammation.

Background Concomitant metabolic dysfunction-associated steatotic liver disease (MASLD) is prevalent in patients with chronic ...

A researcher at the University of Missouri has made a promising breakthrough in the quest to help people with amyotrophic ...

A researcher at the University of Missouri has made a promising breakthrough in the quest to help people with amyotrophic lateral sclerosis (ALS), the neurodegenerative disorder commonly known as Lou ...

An international team led by Jaime de Juan-Sanz at the Paris Brain Institute has shown that slightly increasing the metabolic ...

Yeast, worms, and mice remodel their endoplasmic reticulum early in the aging process. The protective shift offers potential targets to extend healthy lifespan.

A buildup of a structural protein called F-actin inside aging brain cells appears to cripple the cellular waste-clearing machinery that keeps neurons healthy, according to a study in Drosophila fruit ...