Scientists have engineered a lab-on-a-chip system capable of applying precisely controlled mechanical forces to biological materials that mimic the extracellular matrix.

Post-traumatic osteoarthritis develops rapidly after joint injury, yet current treatments largely address symptoms rather ...

This study reports an important and novel finding that TENT5A, an enzyme involved in fine-tuning poly(A) tail length on selected mRNAs, is required for proper enamel mineralization in mice. The ...

A comprehensive review published in Spine Research synthesizes evidence on aggrecan, the core molecule responsible for hydration in spinal discs. The authors present the first comprehensive, 4-part ...

A first in-human, phase I trial examined feasibility as well as safety ...

Neuromuscular diseases comprise a heterogeneous group of disorders characterized by progressive impairment of muscle function resulting from defects in ...

Together, these findings indicate that astrocytes undergo profound sex- and region-specific adaptations to chronic ethanol, implicating extracellular matrix and glycosaminoglycan remodeling as key ...

The German doctor sold her brand to Puig in January 2024, and has since taken on the role of chief product development ...

Tezepelumab is associated with beneficial changes in nasal polyp gene expression in patients with chronic rhinosinusitis with ...

Repair of open neural tube defects, including myelomeningocele, in the fetus has been shown to improve postnatal outcomes by decreasing the severity of hydrocephalus and, consequentially, reducing the ...