Scientists have engineered a lab-on-a-chip system capable of applying precisely controlled mechanical forces to biological materials that mimic the extracellular matrix.

Post-traumatic osteoarthritis develops rapidly after joint injury, yet current treatments largely address symptoms rather ...

Researchers show how damaged tissue is reshaped to trigger painful bone formation in muscles and tendons CHINA, ...

This study reports an important and novel finding that TENT5A, an enzyme involved in fine-tuning poly(A) tail length on selected mRNAs, is required for proper enamel mineralization in mice. The ...

Senescence. It’s a beautiful-sounding word whose tones suggest it should be a perfume or an essential oil. But that’s not even close. Senescence is the loss of a cell’s power to divide and grow, thus ...

Recent works in mechanobiology have investigated overarching changes in cell behavior in response to extracellular matrix (ECM) stiffness. Nonetheless, little is known about how key metabolic pathways ...

A groundbreaking study led by Children's Hospital Los Angeles has found a novel mechanism behind neuroblastoma progression: the shape and structure of the extracellular matrix. The study, led by ...

Is this real life? Is this just fantasy? A growing number of scientists are suggesting that the idea that we are all living in a simulation may not be completely far-fetched. Simulation theory is the ...

The Nature Index 2025 Research Leaders — previously known as Annual Tables — reveal the leading institutions and countries/territories in the natural and health sciences, according to their output in ...

Fascia of live mouse pancreas, in which the extracellular matrix is labeled with Rhobo6 (red) and nuclei are labeled with Hoechst (cyan). Maximum intensity projection shown. Credit: Fiore et al.