Multitarget stool DNA tests — which are becoming more popular in the United States — have shown increased sensitivity over fecal immunochemical tests (FITs) for early colorectal cancer (CRC) screening ...

A mailed fecal immunochemical test (FIT) outreach followed by patient navigation for those with a positive test increased colorectal cancer (CRC) screening participation at 6 months compared with ...

Initiating FIT screening at ages 40-49 reduces CRC mortality by 39% and incidence by 21% compared to starting at age 50. CRC incidence is rising among younger populations, with a 500% increase in ...

FIT outperformed cfDNA in detecting advanced precancerous colorectal lesions, showing higher sensitivity and specificity. Blood-based tests offer easier implementation and potentially higher adherence ...

People invited to undergo FIT were more likely to participate in colorectal cancer screening compared with those invited to undergo colonoscopy. FIT was noninferior to colonoscopy for colorectal ...

Adding a deadline to a mailed invitation for FIT colorectal cancer screening resulted in improved return rates. The highest return rate was seen with a 2-week deadline. This intervention can be easily ...

Colonoscopy may be inconvenient and require planning, but the consequence and therapy for cancer is far more burdensome.

Studies show higher completion rates for mt-sDNA testing and the positive impact of patient navigation in expanding access to underserved and older populations “Exact Sciences’ research at ACG 2025 ...

Colon cancer is the second-deadliest cancer in the US, partly due to low screening rates. New and emerging screening tools, like blood and breath tests, may offer alternatives to in-office screenings.