A study published today in the journal Developmental Cell uncovers new insights into how the heart forms during the earliest stages of embryonic development.

When planning a trip, it's rare that you don't have a choice of route. One may be more direct, another more scenic; but regardless of the time or route taken, the destination is the same. This concept ...

Although Otx2 has been a topic of research for over 3 decades, the role of Otx2 expressed in the brain-forming anterior epiblast during gastrulation has not been clarified. We focused on epiblast ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. During gastrulation, mesodermal cells derived ...

Researchers at UCL and the Francis Crick Institute have, for the first time, identified the origin of cardiac cells using 3D images of a heart forming in real-time, inside a living mouse embryo. For ...

The myocardium of the heart is composed of multiple highly specialized myocardial lineages, including those of the ventricular and atrial myocardium, and the specialized conduction system.

Scientists at the University of California, Santa Cruz (UCSC), used CRISPR to engineer cellular models of embryos that mimic what happens in the first few days after reproductive cells meet. These ...

Version of Record: This is the final version of the article. In chicken embryos, the counter-rotating migration of epiblast cells on both sides of the forming primitive streak (PS), a process referred ...

It’s one of life’s most defining moments—that crucial step in embryonic development, when an indistinct ball of cells rearranges itself into the orderly three-layered structure that sets the stage for ...

It's one of life's most defining moments - that crucial step in embryonic development, when an indistinct ball of cells rearranges itself into the orderly three-layered structure that sets the stage ...