Despite substantial advances in guideline-directed medical therapy, recurrent hospitalization remains a persistent challenge in the management of congestive heart failure (CHF). Fluid overload is ...

Little is known about the initial dosing of loop diuretics among patients hospitalized for heart failure and its association with outcomes. Despite decades of experience with intravenous loop ...

The most common downstream events included worsening kidney function, orthostasis, electrolyte abnormalities, and falls. HealthDay News — The potential downstream harms in the gabapentinoid ...

Some medications can quietly affect how your body absorbs or uses specific nutrients. Knowing which ones may influence your nutrient levels can help you stay ahead of any changes and support your ...

Clinicians may fail to recognize common side effects of drugs like gabapentin — which are frequently prescribed for nerve pain — leading them to prescribe unnecessary medications that cause yet more ...

Background Acute heart failure (AHF) is a severe clinical syndrome associated with high morbidity and mortality. Effective management of congestion is a primary treatment goal and often requires ...

Background: Outcomes of patients with acute decompensated heart failure (ADHF) remain suboptimal. Loop diuretics are first-line therapy in ADHF patients and low urinary spot sodium (spot-U Na) after ...

Panelists discuss how β-blockers remain foundational therapy for heart failure with reduced ejection fraction (using evidence-based agents like carvedilol, metoprolol succinate, or bisoprolol) with ...

Credit: SQ Innovation. The Lasix ONYU is a drug-device combination therapy that allows for subcutaneous infusion of furosemide, a loop diuretic. The pre-programmed device delivers 30mg of furosemide ...

Early recognition of diuretic resistance is essential for preventing avoidable admissions and progression of acute decompensated heart failure. This Perspective synthesises current evidence and ...

ACE inhibitors and ARBs have little to no effect on cholesterol levels. Older beta-blockers and high-dose diuretics may slightly raise LDL cholesterol and lower HDL cholesterol. These changes are ...

1. First intranasal loop diuretic approved by the FDA for heart, kidney, and liver disease patients. 2. Clinical trials showed comparable efficacy to intravenous dosing with more convenient outpatient ...