The most consistent biological findings in patients with depression are abnormalities in the hypothalamic–pituitary–adrenal (HPA)-axis, which can be measured ...

Picking the Right Patient for Human Epidermal Growth Factor Receptor 3–Targeted Therapy in Platinum-Resistant Ovarian Cancer The Oncology Grand Rounds series is designed to place original reports ...

The hypothalamus–pituitary–target gland axis has been recognized as a fundamental functional framework of the mammalian endocrine system. The anterior pituitary gland synthesizes and secretes multiple ...

Testing of hypothalamic-pituitary-end-organ function has advanced remarkably in recent years. As newer tests are compared to the standard ones, it has become apparent that no single test can determine ...

Levels of thyroid hormones in serum are tightly regulated by the hypothalamic-pituitary-thyroid axis (Figure 1). Hypothalamic TSH-releasing hormone (TRH) is secreted mainly from the paraventricular ...

This article was reviewed by Darragh O’Carroll, MD. Key Takeaways: Enclomiphene boosts natural testosterone production by stimulating the hypothalamic-pituitary-gonadal (HPG) axis, making it a ...

Did you know the brain plays a crucial role in impacting male fertility? The hypothalamus and pituitary gland, two small but crucial parts of the brain, control key hormones that regulate sperm ...