Dysfunction of the intestinal epithelium barrier (DIEB) is frequent and can lead to serious complications in early childhood when diagnosis and clinical intervention are limited, especially in ...

Sample preparation plays a crucial role in bioanalytical analysis involving chromatography. Insufficient sample preparation, such as skipping protein precipitation, phospholipid removal (PLR), ...

Discover how advanced LC-MS/MS can deliver robust, low-maintenance performance for food contaminant testing, enabling faster results, high throughput and reliable accuracy across challenging food ...

A novel LC–MS/MS platform enables ultra-microanalysis of remifentanil, etomidate, and rocuronium in maternal and umbilical serum samples, crucial for perinatal pharmacokinetics. The method achieves ...

Abstract: In recent years, liquid chromatography-mass spectrometry (LC-MS) based quantitative proteomics has demonstrated significant potential. It enables the quantification of relative protein ...

Stable isotope-labeled internal standards are widely used in laboratory-developed clinical mass spectrometry tests. An equal amount of these internal standards is added to all samples in a batch, ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. Non-Commercial (NC): Only non-commercial uses of the work are permitted. No ...

Full-scan MS data from both LC-MS and imaging MS capture multiple ion forms, including their in/post-source fragments. Here we leverage such fragments to structurally annotate full-scan data from ...

Experiment Research Institute, National Agricultural Products Quality Management Service, 141, Yongjeon-ro, Gimcheon-si, Gyeonsnagbuk-do 39660, Korea ...

LC-MS/MS-based metabolomics is an important tool for studying disease-related biomarkers. Conventionally, different strategies have been used to screen biomarkers. However, many studies for biomarker ...