A recent study by the University of Bonn and University Hospital Bonn and the University of Freiburg shows that the ...

A review maps high throughput strategies that link automation, microfluidics, and barcoding into a unified pipeline, enabling faster, more predictive lipid nanoparticle development for genetic ...

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Rice and millet dispersed from the Korean peninsula to the Japanese archipelago, arriving first on the island of Kyushu around three millennia ago, beyond that little is known about their culinary use ...

Background Liver metastasis is a major cause of mortality in patients with colorectal cancer (CRC). Understanding how CRC cells influence the formation of hepatic premetastatic niches (PMNs) is ...

Capstan Therapeutics scientists demonstrate that lipid nanoparticles can engineer CAR T cells within the body without laboratory cell manufacturing and ex vivo expansion. The method using targeted ...

Bridge-like lipid transporters (BLTPs) have recently been revealed as key regulators of intraorganellar lipid trafficking, with their loss being associated with defective synaptic signalling and ...

New research suggests that decreased activity of ELOVL2 -- a key enzyme in lipid metabolism -- accelerates white blood cell aging and alters genes associated with the onset of blood cancers. Our ...

Decreased activity of the enzyme ELOVL2 accelerates white blood cell aging and alters the expression of cancer-associated genes, new research suggests. Image depicts immune cells in the bone marrow, ...

To create A1 lipid nanoparticles for delivering mRNA to target cells, scientists at the University of Pennsylvania used A3 coupling. A3 refers to the amine–aldehyde–alkyne coupling reaction, which the ...

Genetically Proxied Lipid-Lowering Drug Target Perturbation and Ischemic Stroke Risk in European and African Ancestry Individuals: Mendelian Randomization Study ...