The most common downstream events included worsening kidney function, orthostasis, electrolyte abnormalities, and falls. HealthDay News — The potential downstream harms in the gabapentinoid ...

The analysis included 120 veterans (66 years and older) who potentially experienced the gabapentinoid-LD prescribing cascade. HealthDay News — The potential downstream harms in the gabapentinoid ...

TUESDAY, Dec. 9, 2025 (HealthDay News) -- The potential downstream harms in the gabapentinoid (gabapentin and pregabalin)-edema-loop diuretic (LD) prescribing cascade are commonly overlooked, ...

Background Acute heart failure (AHF) is a severe clinical syndrome associated with high morbidity and mortality. Effective management of congestion is a primary treatment goal and often requires ...

Background: Outcomes of patients with acute decompensated heart failure (ADHF) remain suboptimal. Loop diuretics are first-line therapy in ADHF patients and low urinary spot sodium (spot-U Na) after ...

Panelists discuss how diuretics serve as necessary “bailout therapy” for volume management in heart failure but should not substitute for guideline-directed medical therapy, with emerging evidence ...

Finerenone, a nonsteroidal mineralocorticoid receptor antagonist, demonstrated consistent efficacy and safety regardless of diuretic type or dose and reduced overall diuretic requirements in patients ...

A new analysis suggests that finerenone (Kerendia), a newer heart failure medication, may help older adults rely less on high doses of water pills. The findings come from the large FINEARTS-HF ...

Finerenone reduced heart failure events and cardiovascular deaths in patients with HFmrEF or HFpEF when used with diuretics. The study found finerenone reduced hypokalemia risk but increased ...

Thiazides, thiazide-like and loop diuretics are commonly prescribed to manage hypertension and heart failure. The main mechanism of action of these diuretics involve inhibition of Na + reabsorption in ...