Methotrexate injection, a treatment for certain autoimmune diseases and cancers, can lead to various side effects. These range from common, mild reactions such as headache and nausea to serious, ...

ABSTRACT: Purpose: To evaluate a therapeutic monitoring strategy for ectopic pregnancies treated with methotrexate (MTX) injection based on hCG level kinetics, in order to identify patients at low ...

Objective: Low-dose methotrexate (LD-MTX), a treatment regimen involving weekly doses ≤20 mg, is widely used in rheumatoid arthritis. Methotrexate (MTX) is primarily excreted via the kidneys. However, ...

Alan J. Franklin, MD, PhD, FASRS, presented, "Postoperative methotrexate injections decrease reoperation rate and improve vision following vitrectomy for PDR and complex retinal detachments," at the ...

ADX-2191 is an investigational methotrexate injection for primary vitreoretinal lymphoma, a rare cancer with no FDA-approved treatments. The FDA requires a single clinical trial, alongside literature ...

Randomized, Open-Label, Phase III Study of Tilsotolimod in Combination With Ipilimumab Versus Ipilimumab Alone in Patients With Advanced Refractory Melanoma (ILLUMINATE-301) R1 compared induction ...

High-dose methotrexate (HD-MTX) toxicity represents a significant clinical challenge in oncology, commonly resulting in acute kidney injury (AKI), myelosuppression, and potentially life-threatening ...