Background The association between lower adult lung function and increased cardiovascular comorbidity has not been adequately explained. We investigated whether shared developmental signalling ...

“We know the genes, but not their functions.” To resolve this long-standing bottleneck in microbial research, a joint research team has proposed a cutting-edge research strategy that leverages ...

The term “metagenome” refers to the collective genetic material of microbial organisms within a given environment, which can be observed within or among individual “microbes” (single individuals or ...

Study finds CRISPR/Cas gene editing causes “chromatin fatigue” – another surprise mechanism by which it can produce unwanted changes in gene function. Report: Claire Robinson and Prof Michael Antoniou ...

Revolutions in gene therapy are rapidly changing the landscape of modern medicine. Revolutions in gene therapy are rapidly changing the landscape of modern medicine, forcing society and science alike ...

A cat named "Noggin" now has a helmet to protect her own noggin thanks to the help of a college student in Tennessee. A cat named "Noggin" now has a helmet to protect her own noggin thanks to the help ...

Instead of requiring personalized gene edits for each patient, the new approach could create a standardized method to use for many diseases. By Pam Belluck and Carl Zimmer Gene-editing therapies offer ...

Abstract: Large tree-of-life (ToL) scale databases of microbial genomes are powerful resources for exploring genome structure and function from a phylogenomic context. Despite the growing availability ...

Contributed by William G. Kaelin Jr.; received May 23, 2024; accepted August 27, 2024; reviewed by Patricia L. Dahia and John M. Maris ...

A gene therapy that targets a form of retinitis pigmentosa showed a signal to improve retinal function for up to 3 years after treatment, according to a small clinical trial. The phase 2 SKYLINE trial ...

Bone morphogenetic proteins (BMPs) play many roles in mammalian cardiac development. Here we address the functions of Noggin, a dedicated BMP antagonist, in the developing mouse heart. In early ...