Discover how white matter changes in the brain can predict aging trajectories and cognitive decline in individuals.

Tau proteins play an important role in our normal brain function, mainly by helping to stabilize neurons in the brain. But in Alzheimer’s disease, tau proteins can misfold and tangle inside neurons.

When myelin breaks down, white matter in the brain deteriorates, a change commonly seen with aging. At the same time, microglia, the brain’s primary immune cells, can shift from protective responders ...

New noninvasive tools reveal that subtle shifts in brain blood flow and oxygen use may mirror key markers of Alzheimer’s risk ...