More than two hundred metabolic enzymes, many of which are normally tasked with producing energy in the mitochondria, are also found sitting directly on top of human DNA, according to a study ...

When it comes to neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and certain forms of dementia, researchers have known that protein quality control and damage to the nuclear ...

In rare genetic ALS tied to VCP mutations, an overactive “cleanup” system may damage nerve cells. The study links VCP overactivity to nuclear pore disruption and abnormal TDP-43 location in cells.

Nuclear pore complexes are more dynamic than previously thought, reshaping our understanding of a vital transport process in cells. An international study led by the University of Basel (Switzerland) ...

In situ model of the nuclear pore complex transport barrier: Tethered within the pore are highly dynamic protein threads termed FG Nups (green). Under physiological conditions, cargo-carrying ...

Iran’s foreign minister said his country would halt plans for a reinstatement of nuclear inspections at a time of heightened concern over Iran’s enriched uranium. By Erika Solomon Iran said Thursday ...

An international team of scientists has unveiled the most comprehensive model yet that explains how cells control the flow of materials in and out of their nuclei—solving one of biology's oldest ...

Plasmodesmata are channels that allow cell-cell communication in plants; based on the functional similarities between facilitated transport within plasmodesmata and into the nucleus, the authors ...