Oxidative stress is a direct consequence of an excess in the body of so-called free radicals—reactive, unstable molecules that contain oxygen. Free radicals are normal metabolic by-products and also ...

Scientists at Oregon State University have developed a new nanomaterial that triggers a pair of chemical reactions inside cancer cells, killing the cells via oxidative stress while leaving healthy ...

This is an important study that utilized in vivo optical measurements of the cortical metabolic rate of O2 and blood flow, as well as measurements in isolated mitochondria to assess the uncoupling of ...

Insulin resistance (IR) is a core pathological feature of type 2 diabetes mellitus (T2DM) and is closely associated with mitochondrial dysfunction in insulin-sensitive tissues, including skeletal ...

Vandria has taken a step forward in its bid to bring a new kind of Alzheimer’s treatment into the clinic. The Lausanne-based company shared first-in-human data for its lead candidate VNA-318 ahead of ...

In a bid to better understand how cancer cells power their explosive growth and spread, scientists at Johns Hopkins Medicine say they have shed new light on the location and function of ...

College of Food Science and Engineering, Jilin Agricultural University, Changchun 130018, China Jilin Province Innovation Center for Food Biological Manufacture, Jilin Agricultural University, ...

Alzheimer’s disease (AD) is a progressive neurodegenerative condition marked by synaptic loss, memory decline, and brain atrophy. Oxidative stress plays a pivotal role in the pathogenesis of AD by ...

The most frequent human enzyme deficiency involves glucose-6-phosphate dehydrogenase (G6PD), the committed enzyme of the oxidative pentose phosphate pathway. Mild G6PD deficiency protects against ...

Neoadjuvant lenvatinib plus pembrolizumab for resectable clear-cell renal cell carcinoma (PELUR): A prospective phase 2 study. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I.

Signal transducer and activator of transcription (STAT) signaling is central to immune regulation and tissue homeostasis, yet how its activation enables cells to distinguish between different ...