Introduction The commonly used frequentist paradigm of null hypothesis statistics testing with its reliance on the p-value and the corresponding notion of ‘statistical significance’ has been under ...

Objectives We estimated the extent of the disparity between statistical significance and clinical importance in published randomised controlled trials (RCTs), and explored factors associated with this ...

A century ago, two oddly domestic puzzles helped set the rules for what modern science treats as "real": a Guinness brewer charged with quality control and a British lady insisting she can taste ...

Monoclonal gammopathy of undetermined significance (MGUS) is a premalignant plasma-cell disorder present in approximately 5% of the general population over the age of 50 years. MGUS is characterized ...

Randomized‐controlled trial evidence has demonstrated that minimally invasive intracerebral hemorrhage (ICH) evacuation can improve outcomes in properly selected patients. Yet, there remains a need to ...

The Alberta Stroke Program Early Computed Tomography Score and core volume on preoperative imaging are key predictors of clinical outcomes following endovascular therapy in patients with a large ...

Growing evidence suggests that corticospinal tract (CST) damage and microstructural integrity are key predictors of post-stroke motor impairment. However, their combined clinical utility—particularly ...

Levels of immune responses in tertiary lymphoid structures of non-small cell lung cancer (NSCLC) and association with survival. Predication of clinical outcomes of advanced cutaneous squamous cell ...

The following is a summary of “An Investigation of Corticospinal Tract Microstructural Integrity in ARSACS Using a Profilometry MRI Analysis: Results From the PROSPAX Study,” published in the April ...

DARIEN, IL — The American Academy of Sleep Medicine has released a new position statement emphasizing the clinical significance of sleepiness and its impact on performance, health, mood, safety, and ...

A new Georgetown University Medical Center study exploring a new brain imaging technique is bringing stroke experts a step closer to better tailoring rehabilitation.