Take a look at the mechanism and the variables behind decarboxylation, to make sure you get higher the next time you make edibles. THC, and all cannabinoids, starts out with an acid group that ...

Oxidative decarboxylation of pyruvate to form acetyl–coenzyme A, a crucial step in many metabolic pathways, is carried out in most aerobic organisms by the multienzyme complex pyruvate dehydrogenase.

Enzymes that use the cofactor thiamin diphosphate (ThDP, 1), the biologically active form of vitamin B 1, are involved in numerous metabolic pathways in all organisms. Although a theory of the ...