The start-up Function will send practically anyone to a lab for extensive medical testing, no physical required. Is that a good thing? By Kristen V. Brown As Kimberly Crisp approached middle age, ...

MINNEAPOLIS -- The small-molecule drug candidate danicamtiv showed promise for activating myosin in gene-related dilated cardiomyopathy (DCM), based on a small phase IIa study. Suggesting boosted ...

Hypertrophic cardiomyopathy (HCM) is a genetic disorder in the heart caused by variants in sarcomeric proteins that disrupt myocardial function, leading to hypercontractility, hypertrophy, and ...

The Nature Index 2025 Research Leaders — previously known as Annual Tables — reveal the leading institutions and countries/territories in the natural and health sciences, according to their output in ...

Hypertrophic cardiomyopathy (HCM) is caused by pathogenic variants in sarcomere protein genes that evoke hypercontractility, poor relaxation, and increased energy consumption by the heart and ...

This convincing study demonstrates a potentially important role for the factor Numb in skeletal muscle excitation–contraction coupling since a Numb knockout reduced contractile force. The authors thus ...

This convincing study demonstrates a potentially important role for the factor Numb in skeletal muscle excitation-contraction coupling. Numb knockout reduced contractile force. The authors thus ...

Illustration of the interacting thick and thin filaments in the cardiac sarcomere based on structural cryo electron-tomography data. Credit: MPI of Molecular Physiology Scientists captured the first ...

The human heart, often described as the body's engine, is a remarkable organ that tirelessly beats to keep us alive. At the core of this vital organ, intricate processes occur when it contracts, where ...

Atrial fibrillation, heart failure and stroke – hypertrophic cardiomyopathy can lead to many serious health conditions and is a major cause of sudden cardiac death in people younger than 35. „The ...

Please provide your email address to receive an email when new articles are posted on . A first-in-human phase 1 trial is testing a novel gene therapy for hypertrophic cardiomyopathy. The one-time ...