Proteinuria affects most people with complement 3 glomerulopathy (C3G). Protein in urine is one of the strongest indicators of disease progression. Reducing proteinuria can slow the progression of C3G ...

The complement system is an innate immune response that leads to increased inflammation. The drug pegcetacoplan—a complement inhibitor—was approved for medical use in the United States in 2021 to ...

Department of Rheumatology, Toronto University, Toronto, ON, Canada. Department of Rheumatology, Toronto University, Toronto, ON, Canada. Department of Internal Medicine, Qatif Central Hospital, Qatif ...

Novo Nordisk is paying $240 million for global rights to a Phase 3-ready drug from Omeros that could rival immune disorder medications currently available from companies such as AstraZeneca, Novartis, ...

Complement 3 glomerulopathy (C3G) is a rare kidney disease that affects your body’s innate immune system (complement system). Complement 3 glomerulopathy (C3G) is a kidney disease that’s caused by ...

Aptamer Group plc, a developer of next-generation synthetic binders for the life sciences industry, has signed a new therapeutic development agreement with Invizius, a clinical-stage biotechnology ...

Among people with sickle cell disease—an inherited blood disorder—acute chest syndrome (ACS) is the leading cause of death. The condition is the result of red blood cells becoming stiff, sticky, and ...

Scientists at the University of Pennsylvania have uncovered the mathematical rules that govern one of the body’s oldest and most important immune system defenses, the complement system, according to ...

Kawasaki Disease (KD) is an acute febrile systemic vasculitis of unknown etiology and the leading cause of acquired heart disease among children. The complement system is a major component of innate ...

A team of scientists has uncovered how an ancient immune system, the complement system, decides when to launch an attack—revealing a hidden mathematical tipping point based on the spatial density of ...

In the 1951 general election Labour and the Conservatives between them secured 98% of the vote. By 2024 that had dropped to 59%, and polling suggests support for the two main parties has continued to ...