Correspondence to Prof Min Chen, Renal Division, Peking University First Hospital, Peking University, Institute of Nephrology, Beijing 100034, China; chenmin74{at}sina.com Although corticosteroid and ...

Renal tubulointerstitial disease (TID) encompasses a range of disorders that damage the kidney tubules and interstitium, leading to inflammation, fibrosis, and ultimately chronic kidney disease ...

Introduction: Feline CKD is associated with an increase in the pro-fibrotic enzyme, transglutaminase 2 (TG2), in the kidney tubulointerstitium. Hypoxia is pivotal factor for the development of CKD, ...

Introduction: Renal dysfunction, defined as lower estimated glomerular filtration rate (eGFR), have been shown to be related to cardiovascular events in patients with myocardial infarction (MI).

The following is a summary of “Development of a multiple urinary biomarker model to predict the tubulointerstitial fibrosis area in patients with primary IgA Nephropathy,” published in the March 2025 ...

Studies investigating what is damaging the kidney in lupus nephritis point to tubulointerstitial inflammation as an important risk factor. Tubulointerstitial inflammation in patients with lupus ...

ABSTRACT: IgG4 disease is an immune-mediated disorder characterized by fibroinflammatory masses that can infiltrate multiple organ systems. Renal involvement is considered one of the key features of ...

TUCSON, Ariz., Sept. 19, 2024 — Critical Path Institute (C-Path) is thrilled to announce its Polycystic Kidney Disease Outcomes Consortium (PKDOC) has been awarded an Autosomal Dominant ...

Rates of acute kidney injury and tubulointerstitial nephritis associated with anticancer therapy have increased worldwide since 2010, attributable mainly to targeted therapies and immunotherapies.

Chronic kidney disease (CKD) is a public health challenge that affects more than 800 million people worldwide. 1 CKD can be caused by a variety of disease processes. Many causes are difficult to ...

In conclusion, our study introduces innovative strategies for developing renal-targeting drug delivery systems in preclinical research. While this study focuses on tubulointerstitial fibrosis, future ...