A new brain-imaging study has revealed how ketamine produces its fast antidepressant effects in people with treatment-resistant depression. Researchers tracked changes in a critical brain receptor ...

For decades, treating major depression has involved a frustrating cycle of trial and error, with patients cycling through medications and therapies while clinicians rely on symptoms and intuition more ...

Major depressive disorder (MDD) is a major global health problem and one of the leading causes of disability. About 30% of people diagnosed with ...

In recent years, a drug called ketamine has attracted attention because it can reduce depressive symptoms very quickly. Unlike traditional antidepressants, which may take weeks to work, ketamine can ...

A surprising energy imbalance in the brain and blood cells may offer a new way to detect and treat depression earlier.