The authors conclude that mRNA vaccines “induce a gene-altering [mode of action], reprogramming host expression programs” that go far beyond inflammatory responses to Spike protein. Effects include ...

Better mRNA release inside cells boosts vaccine and gene editing performance, enabled by redesigned lipid molecules that grip ...

Scientists at the University of Chicago have built a lipid nanoparticle system that delivers mRNA directly to ...

Scientists developed a new mRNA platform that keeps vaccines and therapies effective in older adults and patients with obesity, where current treatments often lose potency. (Nanowerk News) Researchers ...

RIKEN researchers have discovered how an enzyme modifies gene expression by targeting certain stretches of messenger RNA ...

Messenger RNA, or mRNA, vaccines entered the public consciousness when they were introduced during the COVID-19 pandemic, and both Pfizer-BioNTech and Moderna used the technology in developing their ...

Lipid nanoparticle-delivered messenger RNA encoding anti-PD-L1 nanobodies has reduced tumour growth in sporadic and colitis-associated colorectal cancer models, with quadruple constructs that ...

Researchers developed an mRNA delivery system designed to improve embryo implantation. This approach could enhance ART outcomes and address uterine-factor infertility, with pre-clinical studies ...