The mechanism of action of mRNA vaccines goes far beyond harnessing host cellular machinery to produce antigenic proteins to spur immunity, write Nicolas Hulscher, M.P.H., Peter A. McCullough, M.D., M ...

Better mRNA release inside cells boosts vaccine and gene editing performance, enabled by redesigned lipid molecules that grip ...

Naked mRNA administration in the testes rescues sperm function, demonstrating a potential therapeutic approach for genetic male infertility.

Lipid nanoparticle-delivered messenger RNA encoding anti-PD-L1 nanobodies has reduced tumour growth in sporadic and colitis-associated colorectal cancer models, with quadruple constructs that ...