USMLE High-Yield Questions on Instagram: "Mood stabilized. Bladder destabilized 😭💀 ⸻ ✅ Explanation (with answer) Correct answer: C) Nephrogenic diabetes insipidus Lithium causes nephrogenic DI by making the kidneys unresponsive to ADH at the collecting ducts. Key clues: • Polyuria + polydipsia • On lithium • Normal glucose (rules out osmotic diuresis) Lithium interferes with ADH signaling → inability to concentrate urine → excessive dilute urine output. High-yield: persistent cases can be trea

Rude Anatomy on Instagram: "🧠 Lithium is a true mood stabilizer for bipolar disorder Treats acute mania and provides long-term maintenance One of the few psychiatric meds shown to reduce death from self-harm, even independent of mood control Not a sedative Not a serotonin booster ⚠️ Narrow therapeutic window — levels matter Neurologic symptoms = think lithium toxicity Chronic use affects kidneys (polyuria, nephrogenic DI) and thyroid (hypothyroidism) Monitoring lithium levels, renal function, a