Please tell me that’s not CSF… A CSF leak is when cerebrospinal fluid (CSF) escapes through a tear or hole in the dura, the membrane surrounding the brain and spinal cord. This leakage can cause a headache that worsens when you sit or stand and improves when you lie down. Causes include head or spine injuries, certain medical procedures like spinal taps, or spontaneous leaks with no known cause. A CSF leak creates an opening between the central nervous system and the outside world, increasing th